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CRTH2
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN24302 | MK-7246 | 1218918-62-7 | MK-7246 is a potent and selective CRTH2 antagonist with Ki value of 2.5nM. |
CSN20221 | MK-2305 | 2101206-49-7 | MK-2305 is a GPR40 partial agonist lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production. |
CSN18830 | Fevipiprant | 872365-14-5 | Fevipiprant is a selective, potent, reversible competitive CRTh2 antagonist with an in vitro dissociation constant KD value of 1.1nM at the CRTh2 receptor and an IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood. |
CSN22382 | CRTh2 antagonist 1 | 1379445-54-1 | CRTh2 antagonist 1是 CRTh2 的拮抗剂,IC50 值为89 nM。 |
CSN26623 | CAY10471 Racemate | 844639-57-2 | CAY 10471 is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 binds to the human CRTH2/DP2, DP1, and TP receptors with Ki values of 0.6, 1200, and >10,000 nM. Cat#531655 is a racemic mixture of CAY10471. |
CSN16482 | AZD1981 | 802904-66-1 | AZD1981 is a potent and selective CRTh2 antagonist and displaces radio-labelled PGD2 from human recombinant DP2 with high potency (pIC50 = 8.4). |
CSN22681 | Vidupiprant | 1169483-24-2 | AMG 853 is a potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist (IC50 values are 8 and 35 nM, respectively in plasma). |
CSN25231 | AM211 | 1175526-27-8 | AM211 is a potent and selective prostaglandin D2 receptor type 2 antagonist with IC50 value of 4.9nM. |
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